A toothache is a very common dental condition. Toothaches can be caused by many factors, including: food and drink, tooth decay, tooth sensitivity, and gum disease. Did you know that tooth decay can lead to more serious dental problems? It can lead to tooth loss, oral infections, and even serious health problems. If you have a toothache, visit your dentist immediately. A toothache is a very painful condition and can usually be treated, however, if the cause of the pain is not treated it can become much more serious.